Category: Nuclear medicine

Association of CNR1 gene and cannabinoid 1 receptor protein in the human brain by Kyoungjune Pak

We aimed to integrate genomic mapping from brain mRNA atlas with the protein expression from positron emission tomography (PET) scans of type 1 cannabinoid (CB1) receptor and to compare the predictive power of CB1 receptor with those of other neuroreceptor/transporters using a meta-analysis. Volume of distribution (V(T) ) from F18-FMPEP-d2 PET scans, CNR1 gene (Cannabinoid…

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Regenerative inflammation: when immune cells help to re-build tissues by Noemí Caballero-Sánchez

Inflammation is an essential immune response critical for responding to infection, injury, and maintenance of tissue homeostasis. Upon injury, regenerative inflammation promotes tissue repair by a timed and coordinated infiltration of diverse cell types and the secretion of growth factors, cytokines, and lipids mediators. Remarkably, throughout evolution as well as mammalian development, this type of…

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Repercussions of patrilocal residence on mothers’ social support networks among Tsimane forager-farmers by Edmond Seabright

While it is commonly thought that patrilocality is associated with worse outcomes for women and their children due to lower social support, few studies have examined whether the structure of female social networks covaries with post-marital residence. Here, we analyse scan sample data collected among Tsimane forager-farmers. We compare the social groups and activity partners…

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Current research topics in FAPI theranostics: a bibliometric analysis by Andor F van den Hoven

CONCLUSION: FAPI research is rapidly expanding from diagnostic studies in malignancies and benign diseases to the first reports of salvage radionuclide therapy. The research activity needs to shift now from low-level-of-evidence case reports and series to prospectively designed studies in homogenous patient groups to provide evidence on how and in which clinical situations FAPI theranostics…

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In vivo methods for imaging blood-brain barrier function and dysfunction by William James Harris

The blood-brain barrier (BBB) is the interface between the central nervous system and systemic circulation. It tightly regulates what enters and is removed from the brain parenchyma and is fundamental in maintaining brain homeostasis. Increasingly, the BBB is recognised as having a significant role in numerous neurological disorders, ranging from acute disorders (traumatic brain injury,…

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The role of single fraction Gamma Knife radiosurgery for intraventricular central neurocytomas and the utility of F-18 fluroethyltyrosine: two case reports by Michaela Dedeciusova

CONCLUSIONS: In atypical central neurocytomas, F-18 fluroethyltyrosine could be used as postoperative examination to detect small tumor remnants, follow-up evaluation following the Gamma Knife surgery or, in select cases, following surgical resection. The role of MIB-1 is important in therapeutic decision-making, as tumors with MIB-1 exceeding 2% are characterized by more aggressive clinical course. Single-fraction…

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