Category: CoViD

Clinical and Imaging Evaluation of COVID-19-Related Olfactory Dysfunction by Eslam Hamed Elsayed Abdou

CONCLUSION: The average olfactory bulb volumes were significantly higher in the patients’ group compared to the control group, indicating significant edema and swelling in the olfactory bulb in patients with COVID-related olfactory dysfunction. Furthermore, in most patients, no sinonasal symptoms such as nasal congestion or rhinorrhea were reported, and similarly, no radiological evidence of sinusitis…

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Insight into vaccination and meteorological factors on daily COVID-19 cases and mortality in Bangladesh by Mohammad Nayeem Hasan

The ongoing COVID-19 contagious disease caused by SARS-CoV-2 has disrupted global public health, businesses, and economies due to widespread infection, with 676.41 million confirmed cases and 6.77 million deaths in 231 countries as of February 07, 2023. To control the rapid spread of SARS-CoV-2, it is crucial to determine the potential determinants such as meteorological…

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Dietary fish intake increased the concentration of soluble ACE2 in rats. Can fish consumption reduce the risk of COVID-19 infection through interception of SARS-CoV-2 by soluble ACE2? by Maria O’Keeffe

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the cells after binding to the membrane-bound receptor angiotensin-converting enzyme 2 (ACE2), but this may be prevented through interception by soluble ACE2 (sACE2) or by inhibition of the ACE2 receptor, thus obstructing cell entry and replication. The main objective of this study was to investigate if…

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Prognosis Markers and Patient Health Behavior of COVID-19 on Treatment in Turkey by Bozkurt Nurgül

Objective: During the COVID-19 outbreak, the medical sector services to the public were reportedly not appropriate. Due to the novelty of the disease, the patients were not aware of the right treatment and what health facilities were required. Method: The current research is designed to determine the relationship between prognosis markers and patient health behavior…

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Association of funding and conflicts of interest on outcomes reported in published studies of Covid-19 by Snehalata Gajbhiye

An outbreak of the Covid-19 has led to substantial mortality globally. The entire world is carrying out studies to understand the pathophysiology, clinical features, diagnosis and treatment of Covid-19. We investigated the possible association of type of funding, corporate or academic, and conflict of interests on the outcomes reported in clinical trials on Covid-19. Methods:…

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Pseudoknot-targeting Cas13b combats SARS-CoV-2 infection by suppressing viral replication by Daseuli Yu

CRISPR-Cas13-mediated viral genome targeting is a novel strategy for defending against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Here, we generated mRNA-encoded Cas13b targeting the open reading frame 1b (ORF1b) region to effectively degrade the RNA-dependent RNA polymerase gene. Of the 12 designed CRISPR RNAs (crRNAs), those targeting the pseudoknot site upstream of ORF1b…

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